Vitamin B1 May Ease Alcohol-Related Headaches.

In 2025, Kuan-Hung Lin and team from Taipei Medical University studied 60 adults with frequent alcohol-related headaches. In a 4-week trial, half got 100 mg daily vitamin B1 (thiamine), while others received a placebo. They measured headache frequency, blood flow via ultrasound, and brain cell health through blood markers, adjusting for alcohol intake and age.

The B1 group had 35% fewer headaches and improved brain blood flow (cerebral velocity up 12%). Blood markers showed less hippocampal neuron damage, suggesting B1 protects against alcohol’s toxic effects on brain cells and blood vessels.

Consider a vitamin B1 supplement if you get headaches from drinking, but consult a doctor first.