A year-long, double-blind trial published in Nutrients by Yaikwawong et al. (2025) tested 1,500 mg/day of ethanol-extracted curcumin in patients with MASLD. After 12 months, those taking curcumin had significantly lower liver fat, reduced inflammation, less oxidative stress, and improved body measurements—BMI, waist, and body fat percentage all decreased.

A 2025 double-blind, placebo-controlled trial by Lamichhane et al. in Nutrients found that elderly prediabetic adults taking 80 mg/day of curcumin for 12 weeks saw significant reductions in HbA1c, a key marker of long-term blood sugar control.