Amino Acids Can Save Your Muscle While Losing Fat.

In 2025, Cannavaro, Leva, Caturano, Berra, Bonfrate & Conte (Université Clermont Auvergne & CNRS) reviewed research on using amino acid supplements during weight loss. Their Nutrients paper finds that certain amino acids—especially leucine, HMB, and collagen peptides—help protect lean mass when you’re slimming down  .

Why does lean mass matter? It keeps your metabolism revved, strength up, and bones robust—even as you lose weight. The review shows that combining these amino acids with resistance training preserves muscle better than dieting alone. Without them, you risk losing muscle and slowing your metabolism.

While shedding fat, you won’t lose strength or metabolic power if you take amino acids (like 3–6 g leucine or 1–3 g HMB) and lift weights regularly.