A 2025 randomized controlled trial in Nutrients by Sharif et al. showed those who drank tocotrienols experienced better psychological well-being, lowered markers of oxidative stress, increased antioxidant enzymes, and improved genomic stability.

A 2025 feasibility trial by Meinlschmidt et al. studied 54 women with and without obesity after a 10-hour daytime fast. Both groups reported increased hunger and lower satiety, but mood effects differed: women with obesity experienced more depression and anger, while non-obese women mainly reported increased fatigue.