In a review by Dr. John Douillard from LifeSpa.com, drawing on studies like the Rotterdam Study (2004) involving 4,807 adults over 55, vitamin K2's role was examined. K2 activates proteins to direct calcium to bones and away from arteries, preventing stiffness and brittleness. The study found at least 32 mcg daily cut cardiovascular death by 50% and all-cause mortality by 25%.