A 2025 study from Shanghai Jiao Tong University showed that food allergies don’t just cause rashes or stomachaches—they can lead to anxiety, depression, attention issues, and social withdrawal. In this mouse model, food allergy triggered brain inflammation, impaired behavior, and disrupted the gut microbiota.

A 2025 randomized, double-blind, placebo-controlled trial published in Nutrients found that supplementing with 100 mg each of vitamin B1 (thiamine) and B2 (riboflavin) daily for four weeks significantly reduced perceived stress and improved sleep quality in young adults.